I D E N T I F I C A T I O N OF A TOXIC CELLULAR COMPONENT OF GROUP A STREPTOCOCCI AS A COMPLEX OF GROUP- SPECIFIC C POLYSACCHARIDE AND A PROTEIN* BY JOHN H. SCHWAB, PH.D.,

@inproceedings{Schwab2003IDE,
  title={I D E N T I F I C A T I O N OF A TOXIC CELLULAR COMPONENT OF GROUP A STREPTOCOCCI AS A COMPLEX OF GROUP- SPECIFIC C POLYSACCHARIDE AND A PROTEIN* BY JOHN H. SCHWAB, PH.D.,},
  author={John H. Schwab and William James Cromartie and Bob and Roberson},
  year={2003}
}
Chronic multinodular skin lesions were produced in rabbits injected intradermally at a single site with a sterile extract of sonically disrupted Group A streptococcal cells (1). These lesions, which consisted of separate nodules scattered over areas as large as 12 cm. in diameter, presented several remarkable features. The injury to dermal connective tissue was evident within 48 hours after injection, suggesting that the material had a primary toxic effect. The reaction was observed to continue… CONTINUE READING

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