I(2)-mediated carbamate annulation: scope and application in the synthesis of azasugars.

Abstract

The I(2)-mediated carbamate annulation provides an efficient and highly stereoselective route for the synthesis of a variety of pyrrolidines and piperidines, both in the presence and absence of protecting groups. Evidence for the formation of an iodoamine intermediate during the annulation is provided and, for the first time, we explore possible mechanisms… (More)
DOI: 10.1016/j.carres.2012.03.015

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