Hyrtioseragamines A and B, New Alkaloids from the Sponge Hyrtios Species.

  title={Hyrtioseragamines A and B, New Alkaloids from the Sponge Hyrtios Species.},
  author={Yohei Takahashi and Yoshiro Iinuma and Takaaki Kubota and Masashi Tsuda and Mitsuhiro Sekiguchi and Yuzuru Mikami and Jane Fromont and Jun’ichi Kobayashi},
New marine natural products from sponges (Porifera) of the order Dictyoceratida (2001 to 2012); a promising source for drug discovery, exploration and future prospects.
The order Dictyoceratida is a valuable source of novel chemical structures which will continue to contribute to a new era of drug discovery. Expand
Two New 2(1H)-Pyrazinone Derivatives from the Plant Endophyte Streptomyces sp. KIB-H1992
Two new 2(1H)-pyrazinone derivatives, 3,6-diisopropyl-5-methylpyrazin-2(1H)-one (1) and 5(hydroxymethyl)-3,6-diisopropylpyrazin-2(1H)-one (2), were isolated from the fermentation broth of endophyticExpand
Synthesis and characterization of novel iminobenzoates with terminal pyrazine moieties
The paper describes the synthesis of novel iminobenzoates following easy methods while utilizing commercially available starting materials and may possibly be converted to compounds with luminescent and liquid crystalline properties after making suitable changes to the pyrazine moieties. Expand
Bioactive Natural Products of Marine Sponges from the Genus Hyrtios
This review covers the literature until June 2016, providing a complete survey of all compounds isolated from the genus Hyrtios with their corresponding biological activities whenever applicable. Expand
Alkaloids from the Mangrove-Derived Actinomycete Jishengella endophytica 161111
The results showed that compound 9 could be a promising new hit for anti-H1N1 drugs and the absolute configurations of 2–5, 13C nuclear magnetic resonance (NMR) data and the specific rotations of 3–6 were reported here for the first time. Expand


Hyrtioseragamines A and B, new alkaloids from the sponge Hyrtios species.
Two novel alkaloids with a furo[2,3-b]pyrazin-2(1H)-one moiety and a guanidino group, hyrtioseragamines A (1) and B (2), have been isolated from an Okinawan marine sponge Hyrtios species. TheExpand