Hypoxic regions exist in human prostate carcinoma.

  title={Hypoxic regions exist in human prostate carcinoma.},
  author={Benjamin Movsas and J. Donald Chapman and Eric Mark Horwitz and Wayne H. Pinover and Richard Evan Greenberg and Alexandra L. Hanlon and Revathy Iyer and Gerald E. Hanks},
  volume={53 1},
OBJECTIVES The purpose of this study was to characterize, by use of the Eppendorf microelectrode, the extent of hypoxia (range/heterogeneity) in human prostate carcinomas. METHODS Custom-made Eppendorf pO2 microelectrodes were used to obtain PO2 measurements from the pathologically involved side of the prostate, as well as from a region of normal muscle for comparison. Each set of measurements comprised approximately 100 separate readings of pO2, for a total of 2145 individual measurements… CONTINUE READING


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