Hypoxic preconditioning promotes the translocation of protein kinase C ε binding with caveolin-3 at cell membrane not mitochondrial in rat heart.

@article{Yu2015HypoxicPP,
  title={Hypoxic preconditioning promotes the translocation of protein kinase C ε binding with caveolin-3 at cell membrane not mitochondrial in rat heart.},
  author={Hongmei Yu and Zhaogang Yang and Su Fang Pan and Yudan Yang and Jiayi Tian and Luowei Wang and Wei Sun},
  journal={Cell cycle},
  year={2015},
  volume={14 22},
  pages={
          3557-65
        }
}
Protein kinase C has been shown to play a central role in the cardioprotection of ischemic preconditioning. However, the mechanism underlying PKC-mediated cardioprotection is not completely understood. Given that caveolae are critical for PKC signaling, we sought to determine whether hypoxic preconditioning promotes translocation and association of PKC isoforms with caveolin-3. A cellular model of hypoxic preconditioning from adult rat cardiac myocytes (ARCM) or H9c2 cells was employed to… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

Role of IRF4 in the Protection of Metformin-Mediated Sepsis Myocarditis

VIEW 6 EXCERPTS
CITES METHODS & BACKGROUND

MicroRNA-143 promotes cardiac ischemia-mediated mitochondrial impairment by the inhibition of protein kinase Cepsilon

VIEW 7 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

The Effect of Photothermal Therapy on Osteosarcoma With Polyacrylic Acid–Coated Gold Nanorods

VIEW 1 EXCERPT
CITES BACKGROUND

Caveolin-1/-3: therapeutic targets for myocardial ischemia/reperfusion injury

VIEW 1 EXCERPT
CITES BACKGROUND