Hypoxic modulation of L-type Ca(2+) channels in inspiratory brainstem neurones: intracellular signalling pathways and metabotropic glutamate receptors.

@article{Mironov2000HypoxicMO,
  title={Hypoxic modulation of L-type Ca(2+) channels in inspiratory brainstem neurones: intracellular signalling pathways and metabotropic glutamate receptors.},
  author={Sergej L. Mironov and Diethelm W. Richter},
  journal={Brain research},
  year={2000},
  volume={869 1-2},
  pages={166-77}
}
Brief hypoxia (2 min) enhances the activity of L-type Ca(2+) (Ca(L)) channels. The effect is due to glutamate release and concomitant stimulation of metabotropic glutamate receptors of the mGLUR1/5 type [22] [S.L. Mironov, D.W. Richter, L-type Ca(2+) channels in inspiratory neurones and their modulation by hypoxia, J. Physiol. 512 (1998) 75-87.]. Besides… CONTINUE READING