Hypoxic-Preconditioned Bone Marrow Stem Cell Medium Significantly Improves Outcome After Retinal Ischemia in Rats

Abstract

PURPOSE We have previously demonstrated the protective effect of bone marrow stem cell (BMSC)-conditioned medium in retinal ischemic injury. We hypothesized here that hypoxic preconditioning of stem cells significantly enhances the neuroprotective effect of the conditioned medium and thereby augments the protective effect in ischemic retina. METHODS Rats… (More)
DOI: 10.1167/iovs.15-17381

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@inproceedings{Roth2016HypoxicPreconditionedBM, title={Hypoxic-Preconditioned Bone Marrow Stem Cell Medium Significantly Improves Outcome After Retinal Ischemia in Rats}, author={Steven Roth and John C. Dreixler and B. Mathew and Irina V. Balyasnikova and Jacob R. Mann and Venkat Boddapati and Lai Xue and Maciej S. Lesniak}, booktitle={Investigative ophthalmology & visual science}, year={2016} }