Hypoxic-Ischemic Encephalopathy and Therapeutic Hypothermia: The Hemodynamic Perspective.

@article{Giesinger2017HypoxicIschemicEA,
  title={Hypoxic-Ischemic Encephalopathy and Therapeutic Hypothermia: The Hemodynamic Perspective.},
  author={Regan E Giesinger and Liane Jennifer Bailey and Poorva Niteen Deshpande and Patrick McNamara},
  journal={The Journal of pediatrics},
  year={2017},
  volume={180},
  pages={
          22-30.e2
        }
}
Hypoxic-ischemic encephalopathy (HIE) is a severe central nervous system injury in neonates secondary to perinatal asphyxia. It may cause devastating lifelong neurocognitive impairments including cerebral palsy. The introduction of therapeutic hypothermia (TH) as standard therapy for neonates >36 weeks gestational age with HIE has improved patient outcomes and is supported by evidence from both animal studies and large-scale clinical trials in humans. TH has been shown to produce clinically… CONTINUE READING
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