Hypoxic-Ischemic Encephalopathy and Serum Magnesium Monitoring and Maintenance

@article{Bell2016HypoxicIschemicEA,
  title={Hypoxic-Ischemic Encephalopathy and Serum Magnesium Monitoring and Maintenance},
  author={Susan Givens Bell},
  journal={Neonatal Network},
  year={2016},
  volume={35},
  pages={159 - 163}
}
ABSTRACT Magnesium plays important roles in many physiologic functions including protein synthesis, bone development, and cell membrane function. There is some evidence to suggest a role for magnesium sulfate as a therapeutic neuroprotective agent along with therapeutic hypothermia in infants with hypoxic-ischemic encephalopathy, but studies are inconclusive. Ischemic insult and hypothermia may both play a role in altered magnesium levels in this population. 
5 Citations
A randomized controlled trial on the use of magnesium sulfate and melatonin in neonatal hypoxic ischemic encephalopathy.
TLDR
MgSO4 may have an added effect for the reduction in brain injury in infants with HIE who are receiving melatonin in a randomized controlled trial on infants with moderate HIE.
System Specific Effects of Therapeutic Hypothermia with Neonatal Encephalopathy: Pearls for Clinicians
TLDR
There is a paucity of literature that comprehensively identifies causal relationships between the physiologic and biochemical effects of Therapeutic hypothermia, which can leave neonatal clinicians devoid of a comprehensive understanding of the medical management of NE.
Vitamin D as an Adjuvant Therapy in Neonatal Hypoxia: Is it Beneficial?
TLDR
Vitamin D was found to improve the cases of group I as demonstrated by the reduction of serum S100-B levels after vitamin D therapy.
Akut İnmede Risk Faktörü ve Prognoz Üzerine Etkisi ile Magnezyum
TLDR
Bu calisma ile serebrovaskuler olayda magnezyumun degistirilebilir bir risk faktoru olarak degerlendirilmesi ve mortalite uzerine etkisinin olup olmadiginin arastirilmasi planlandi dikkat cekici bir ozellikti.

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