Hypoxia. 4. Hypoxia and ion channel function.

  title={Hypoxia. 4. Hypoxia and ion channel function.},
  author={Larissa A. Shimoda and Jan Pol{\'a}k},
  journal={American journal of physiology. Cell physiology},
  volume={300 5},
The ability to sense and respond to oxygen deprivation is required for survival; thus, understanding the mechanisms by which changes in oxygen are linked to cell viability and function is of great importance. Ion channels play a critical role in regulating cell function in a wide variety of biological processes, including neuronal transmission, control of ventilation, cardiac contractility, and control of vasomotor tone. Since the 1988 discovery of oxygen-sensitive potassium channels in… CONTINUE READING


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