Hypoxia simultaneously alters satellite cell-mediated angiogenesis and hepatocyte growth factor expression.

@article{Flann2014HypoxiaSA,
  title={Hypoxia simultaneously alters satellite cell-mediated angiogenesis and hepatocyte growth factor expression.},
  author={Kyle L Flann and Christopher Rathbone and L C Cole and Xinhua Liu and Ronald E. Allen and Robert P. Rhoads},
  journal={Journal of cellular physiology},
  year={2014},
  volume={229 5},
  pages={572-9}
}
Skeletal muscle regeneration is a multifaceted process requiring the spatial and temporal coordination of myogenesis as well as angiogenesis. Hepatocyte growth factor (HGF) plays a pivotal role in myogenesis by activating satellite cells (SC) in regenerating muscle and likely plays a role as a contributor to revascularization. Moreover, repair of a functional blood supply is critical to ameliorate tissue ischemia and restore skeletal muscle function, however effects of hypoxia on satellite cell… CONTINUE READING
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