Hypoxia regulated gene transcription in human optic nerve lamina cribrosa cells in culture.

Abstract

PURPOSE Vascular hypoperfusion, extracellular matrix remodeling and axon loss are pathological characteristics of the glaucomatous optic nerve head. We report a novel study demonstrating transcriptional responses in optic nerve lamina cribrosa (LC) cells exposed to in vitro hypoxic stress. METHODS Primary cultures of human glial fibrillary acid protein… (More)
DOI: 10.1167/iovs.11-6729

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics