Hypoxia promotes vasculogenic mimicry formation by vascular endothelial growth factor A mediating epithelial‐mesenchymal transition in salivary adenoid cystic carcinoma

@article{Wang2019HypoxiaPV,
  title={Hypoxia promotes vasculogenic mimicry formation by vascular endothelial growth factor A mediating epithelial‐mesenchymal transition in salivary adenoid cystic carcinoma},
  author={Hao-Fan Wang and Sha-Sha Wang and Min Zheng and Lu-ling Dai and Ke Wang and Xiao-lei Gao and Ming-xin Cao and Xianghua Yu and Xin Pang and Mei Zhang and Jing-biao Wu and Jia-shun Wu and Xiao Yang and Ya-Jie Tang and Yu Chen and Ya-Ling Tang and Xin-Hua Liang},
  journal={Cell Proliferation},
  year={2019},
  volume={52}
}
  • Hao-Fan Wang, Sha-Sha Wang, +14 authors Xin-Hua Liang
  • Published in Cell proliferation 2019
  • Biology, Medicine
  • OBJECTIVES To investigate the role of hypoxia in vasculogenic mimicry (VM) of salivary adenoid cystic carcinoma (SACC) and the underlying mechanism involved. MATERIALS AND METHODS Firstly, wound healing, transwell invasion, immunofluorescence and tube formation assays were performed to measure the effect of hypoxia on migration, invasion, EMT and VM of SACC cells, respectively. Then, immunofluorescence and RT-PCR were used to detect the effect of hypoxia on VE-cadherin and VEGFA expression… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 51 REFERENCES

    LRIG1 acts as a critical regulator of melanoma cell invasion, migration and vasculogenic mimicry upon hy‐ poxia by regulating EGFR/ERK‐triggered EMT

    • W Li, Y. Zhou
    • Biosci Rep. 2019;39:BSR20181165
    • 2018