Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.

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@article{Wise2011HypoxiaPI, title={Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.}, author={David R. Wise and P. Ward and Jessica E.S. Shay and Justin R. Cross and Joshua J. Gruber and Uma M Sachdeva and Jesse M Platt and Raymond G Dematteo and M. Celeste Simon and Craig B Thompson}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2011}, volume={108 49}, pages={19611-6} }