Hypoxia on the pulmonary circulation. How and where it acts.

@article{Fishman1976HypoxiaOT,
  title={Hypoxia on the pulmonary circulation. How and where it acts.},
  author={Alfred P. Fishman},
  journal={Circulation research},
  year={1976},
  volume={38 4},
  pages={
          221-31
        }
}
  • A. Fishman
  • Published 1 April 1976
  • Biology, Medicine
  • Circulation research

Figures from this paper

Effects of ATP and LTC4 on hypoxic pulmonary vasoconstriction in isolated rat lungs.

In isolated rat lungs, HPV may be mediated by ATP and LTC4 appears more likely to be a modulator than a mediator of HPV.

Constriction of pulmonary artery by peroxide: role of Ca2+ release and PKC.

The Cardiovascular and Metabolic Effects of Chronic Hypoxia in Animal Models: A Mini-Review

This mini-review considers the various animal models which have been deployed to understand the effects of chronic hypoxia on pulmonary and systemic blood pressure, glucose and lipid metabolism, atherosclerosis, and stroke, and the conceptually, effects, and limitations of the available data.

Chronic Obstructive Pulmonary Disease and the Cardiovascular System: Vascular Repair and Regeneration as a Therapeutic Target

Current knowledge about vascular alterations and production of reactive oxygen species in COPD is summarized to summarize and emphasize the importance of the vasculature for the usually parenchyma-focused view of the pathobiology of COPD.

Evaluation of right ventricular performance and impact of continuous positive airway pressure therapy in patients with obstructive sleep apnea living at high altitude

RV structural abnormalities and RV function impairments were observed in OSAS patients living at moderate high altitude compared to control highlanders and the reversibility of these changes after application of CPAP were further confirmed.

Respiratory Physiology for Intensivists

  • P. Alexander
  • Medicine
    Critical Heart Disease in Infants and Children
  • 2019

Evaluation of Echocardiographic Right Ventricular Deformation Parameters in Patients with Chronic Obstructive Pulmonary Disease

KOAH grubunda SV ser best duvar strain parametrelerinden; SV serbest duvar bazal, mid ve apikal strain değerleri kontrol grubuna kıyasla daha düşük saptandı (her karşılaştırma için p< 0.05 idi).

Title Adrenomedullin is not Related to Acute Hypoxic Pulmonary VascularResponse in Patients with Chronic Respiratory Disease

Title Adrenomedullin is not Related to Acute Hypoxic Pulmonary Vascular Response in Patients with Chronic Respiratory Disease Author(s) Furukawa, Katsuyuki; Ikeda, Satoshi; Iwasaki, Tadasu;
...

References

SHOWING 1-10 OF 127 REFERENCES

Pulmonary circulation in acclimatized man at high altitude

Cardiac catheterization studies have been carried out in 30 acclimatized adults at an altitude of 12,3000 ft in the Peruvian Andes, suggesting that in the high-altitude resident, blood viscosity in a hematocrit range of 40-78% does not significantly affect resistance to blood flow.

Lung Perfusion with Angiotensins I and II

There was a decreased responsiveness of rabbit aorta following repeated exposure to lung perfusate containing angiotensin I, which was assumed to be caused by a substance released from the lungs.

R SMOOTH MUSCLE

The choice of emphasis was strongly influenced by the role of vascular smooth muscle in the development of cardiovascular diseases and also by the belief that a specific field of research serves the general cause of research better by asking it an occasional original question.

Handling of Bioactive Materials by the Lung

THE primitive lung was little more than an air sac containing minute vessels in its walls for gas exchange. It served as an accessory organ of breathing that allowed fishes seeking refuge from oxyg...

Hypoxic Pulmonary Vasoconstriction in the Rat: The Necessary Role of Angiotensin II

The results suggest that an action of angiotensin II that is separate from its pressor activity is specifically required for a significant vasoconstrictor response to hypoxia in isolated rat lungs.

COMPARATIVE EFFECTS OF ACIDOSIS INDUCED BY ACID INFUSION AND CO2 ACCUMULATION

Animals with a similar fall in pH produced by CO2 retention presented signs of marked stimulation of the sympatho-adrenal system, such as increased blood pressure, anuria, elevated catecholamine and glucose blood levels, which indicate the importance of intracellular [H+] changes in the regulation of circulation.

Observations on the Pulmonary Arterial Blood Pressure in the Cat

The experiments seem to warrant the conclusion, that the regulation of the pulmonary blood flow is mainly mediated by a local action of the blood and alveolar gases leading to an adequate distribution of theBlood through the various parts of the lungs according to the effeciency of aeration.
...