Hypoxia mediates increased neutrophil and macrophage adhesiveness to alveolar epithelial cells.

@article{BeckSchimmer2001HypoxiaMI,
  title={Hypoxia mediates increased neutrophil and macrophage adhesiveness to alveolar epithelial cells.},
  author={Beatrice Beck-Schimmer and Ralph C. Schimmer and Caveh Madjdpour and John M. Bonvini and Thomas Pasch and Peter A Ward},
  journal={American journal of respiratory cell and molecular biology},
  year={2001},
  volume={25 6},
  pages={
          780-7
        }
}
Leukocyte infiltration is known to play an important role in hypoxia-induced tissue damage. There is a paucity of information on the role of hypoxia in the expression of adhesion molecules on respiratory epithelial cells. The current studies focus on the adhesion molecules intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1), their expression pattern on alveolar epithelial cells, and their biologic function under hypoxic conditions. Rat alveolar epithelial… CONTINUE READING
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