Hypoxia-inducible factor-1α is essential for hypoxia-induced mesenchymal stem cell mobilization into the peripheral blood.

@article{Liu2011HypoxiainducibleFI,
  title={Hypoxia-inducible factor-1α is essential for hypoxia-induced mesenchymal stem cell mobilization into the peripheral blood.},
  author={Lizhen Liu and Qin Yu and Jie Lin and Xiaoyu Lai and Weijie Cao and Kaili Du and Yingjia Wang and Kangni Wu and Yongxian Hu and Lifei Zhang and Haowen Xiao and Yanping Duan and He Huang},
  journal={Stem cells and development},
  year={2011},
  volume={20 11},
  pages={1961-71}
}
Mobilization of mesenchymal stem cells (MSCs) is a promising strategy for tissue repair and regenerative medicine. The establishment of an appropriate animal model and clarification of the underlying mechanisms are beneficial to develop the mobilization regimens for therapeutic use. In this study, we therefore established a rat MSC mobilization model and investigated the related mechanisms, using continuous hypoxia as the mobilizing stimulus. We found that MSCs could be mobilized into… CONTINUE READING
29 Citations
65 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 65 references

Strategy for Maximizing Therapeutic Efficacy of Adult Stem Cells

  • Philip Lazarovici, Anat Blumenfeld
  • Hanyang Medical Reviews
  • 2011

Similar Papers

Loading similar papers…