Hypoxia-induced changes in radiation sensitivity in human melanoma cells: importance of oxygen-regulated proteins, adenylate energy charge and cell cycle distribution.

@article{Danielsen1997HypoxiainducedCI,
  title={Hypoxia-induced changes in radiation sensitivity in human melanoma cells: importance of oxygen-regulated proteins, adenylate energy charge and cell cycle distribution.},
  author={T. L. Danielsen and R Sk\oyum and Einar K. Rofstad},
  journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology},
  year={1997},
  volume={44 2},
  pages={177-82}
}
BACKGROUND AND PURPOSE The effects of transient hypoxia on the radiation sensitivity of human tumour cells have so far been investigated only to a limited extent, and only up to 12 h after reoxygenation. We irradiated cells shortly after reoxygenation (<1 h) or at prolonged times after reoxygenation (24 h and 48 h) in order to examine possible relationships… CONTINUE READING