Hypoxia-induced apoptosis is blocked by adrenomedullin via upregulation of Bcl-2 in human osteosarcoma cells.

@article{Wu2015HypoxiainducedAI,
  title={Hypoxia-induced apoptosis is blocked by adrenomedullin via upregulation of Bcl-2 in human osteosarcoma cells.},
  author={Xue-yuan Wu and C Hao and Ming Ling and Chi-hua Guo and W. T. Ma},
  journal={Oncology reports},
  year={2015},
  volume={34 2},
  pages={787-94}
}
Adrenomedullin (ADM), a multifunctional regulatory peptide, is potentially induced by hypoxia in physiological and pathological tissues, including many types of malignant tumors. Recent research has demonstrated that ADM expression is highly associated with the prognosis and disease severity of human osteosarcoma. However, the effect of ADM on the apoptosis… CONTINUE READING