Vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF), an endothelial cell (EC)–specific mitogen, stimulates angiogenesis in vivo, particularly in ischemic regions. VEGF/VPF expression by cells of hypoxic tissues coincides with expression of its two receptors, KDR and flt-1 , by ECs in the same tissues. We investigated whether hypoxia… (More)


8 Figures and Tables

Slides referencing similar topics