Hypoxia gene expression signatures as prognostic and predictive markers in head and neck radiotherapy.

@article{Toustrup2012HypoxiaGE,
  title={Hypoxia gene expression signatures as prognostic and predictive markers in head and neck radiotherapy.},
  author={Kasper Toustrup and Brita Singers S\orensen and Line Br\ondum and Jens Overgaard},
  journal={Seminars in radiation oncology},
  year={2012},
  volume={22 2},
  pages={119-27}
}
Reliable methods for identification of hypoxia in radiotherapy-treated tumors have been a desirable aim in radiation oncology for decades. Hypoxia is a common feature of the microenvironment in solid tumors, and it is associated with increased aggressiveness, reduced therapeutic response, and a poorer clinical outcome. In head and neck squamous cell carcinomas, the negative effect of hypoxia on radiotherapeutic response can be counteracted and minimized by applying hypoxic modification to… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

Similar Papers

Loading similar papers…