Hypoxia enhances the angiogenic potential of human dental pulp cells.

  title={Hypoxia enhances the angiogenic potential of human dental pulp cells.},
  author={Andreza Maria F{\'a}bio Aranha and Zhaocheng Zhang and Kathleen G. Neiva and Carlos Alberto de Souza Costa and Josimeri Hebling and Jacques Eduardo N{\"o}r},
  journal={Journal of endodontics},
  volume={36 10},
INTRODUCTION Trauma can result in the severing of the dental pulp vessels, leading to hypoxia and ultimately to pulp necrosis. Improved understanding of mechanisms underlying the response of dental pulp cells to hypoxic conditions might lead to better therapeutic alternatives for patients with dental trauma. The purpose of this study was to evaluate the effect of hypoxia on the angiogenic response mediated by human dental pulp stem cells (DPSCs) and human dental pulp fibroblasts (HDPFs… CONTINUE READING
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