Hypoxia-enhanced derivation of iPSCs from human dental pulp cells.

Abstract

Hypoxia enhances the reprogramming efficiency of human dermal fibroblasts to become induced pluripotent stem cells (iPSCs). Because we showed previously that hypoxia facilitates the isolation and maintenance of human dental pulp cells (DPCs), we examined here whether it promotes the reprogramming of DPCs to become iPSCs. Unlike dermal fibroblasts, early and… (More)
DOI: 10.1177/0022034513502204

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