Hypoxia differentially regulates nutrient transport in rat jejunum regardless of luminal nutrient present.

@article{Kles2002HypoxiaDR,
  title={Hypoxia differentially regulates nutrient transport in rat jejunum regardless of luminal nutrient present.},
  author={Keri A Kles and Kelly A. Tappenden},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2002},
  volume={283 6},
  pages={G1336-42}
}
Aggressive enteral nutrition and poor intestinal perfusion are hypothesized to play an important pathogenic role in nonocclusive small bowel necrosis. This study tests the hypothesis that glucose and glutamine transport are differentially regulated during hypoxia regardless of the luminal nutrient present. Sprague-Dawley rats (247 +/- 3 g; n = 16) were randomized to receive 1 h of intestinal hypoxia or serve as normoxic controls. During this hour, jejunal loops were randomized to receive in… CONTINUE READING

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