Hypoxia depresses nitric oxide output in the human nasal airways.

@article{Haight2000HypoxiaDN,
  title={Hypoxia depresses nitric oxide output in the human nasal airways.},
  author={James S Haight and Wei Qian and Hamid Daya and Paul Chalmers and Noel Zamel},
  journal={The Laryngoscope},
  year={2000},
  volume={110 3 Pt 1},
  pages={429-33}
}
OBJECTIVES The role of oxygen in the nasal air on nasal nitric oxide (NO) output was studied in 13 adult volunteers. METHODS Nasal NO was measured while air containing oxygen (0%-100% in nitrogen) was aspirated through the nasal airway before and after the topical application of xylometazoline. RESULTS The mean nasal NO output of the untreated nose was 507.8 +/- 161.9 nL/min (mean +/- SD) when 21% oxygen was aspirated through the nasal cavities in series and remained unaltered by 100% O2 (P… CONTINUE READING