Hypoxia and angiogenesis in pancreatic cancer.

  title={Hypoxia and angiogenesis in pancreatic cancer.},
  author={Giuseppe S. Garcea and Helena Doucas and Will P Steward and Ashley Robert Dennison and David Paul Berry},
  journal={ANZ journal of surgery},
  volume={76 9},
BACKGROUND Pancreatic cancer remains one of the most lethal of all solid tumours of the gastrointestinal tract. It is characterized by late diagnosis, aggressive local invasion, early metastasis and resistance to chemoradiotherapy. Increasing knowledge regarding the molecular events behind the growth and invasion of pancreatic cancer may lead to new targets for intervention. METHODS A search of Pubmed and Medline databases was undertaken using the keywords pancreatic cancer, gastrointestinal… CONTINUE READING


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