Hypoxia and angiogenesis: regulation of hypoxia-inducible factors via novel binding factors


The mechanisms that regulate angiogenesis in hypoxia or hypoxic microenvironment are modulated by several pro- and antiangiogenic factors. Hypoxia-inducible factors (HIFs) have been established as the basic and major inducers of angiogenesis, but understanding the role of interacting proteins is becoming increasingly important to elucidate the angiogenic… (More)
DOI: 10.3858/emm.2009.41.12.103

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