Hypoxia-Ischemia Stimulates Hippocampal Glutamate Efflux in Perinatal Rat Brain: An In Vivo Microdialysis Study

Abstract

ABSTRACT: We used in vivo microdialysis to determine the impact of a focal hypoxic-ischemic insult on hippocampal amino acid efflux in the immature brain. Microdialysis probes were inserted into the right hippocampus of postnatal d 7 rats. To induce hypoxic-ischemic injury, the right carotid artery was ligated and animals were exposed to 8% oxygen for 2 h… (More)
DOI: 10.1203/00006450-199112000-00021

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