Hypoxia-Induced Increases in Hypoxic Tolerance Augmented by / 3-Hydroxybutyrate in Mice

@inproceedings{Rising2005HypoxiaInducedII,
  title={Hypoxia-Induced Increases in Hypoxic Tolerance Augmented by / 3-Hydroxybutyrate in Mice},
  author={Charlotte Rising and L. G. D'AJecy},
  year={2005}
}
A standard murine model was used to determine whether acute pretreatment exposures to hypoxia could alter ultimate hypoxic survival time. Adult male albino mice (Mus musculus) weighing 25-30 g were subjected to three pretreatment hypoxic exposures (4.5% O2, balance N2) of increasing duration (90, 120, and 150 seconds) with 300 seconds of normoxia between each pretreatment exposure and before testing of hypoxic survival time. Acute pretreatment exposures to hypoxia significantly increased mean… CONTINUE READING