Hypoxia/Reoxygenation Cardiac Injury and Regeneration in Zebrafish Adult Heart

@inproceedings{Parente2013HypoxiaReoxygenationCI,
  title={Hypoxia/Reoxygenation Cardiac Injury and Regeneration in Zebrafish Adult Heart},
  author={Valeria Parente and Serena Balasso and Giulio Pompilio and Lorena Verduci and Gualtiero Ivanoe Colombo and Giuseppina Milano and Uliano Guerrini and Michele Frigerio and Franco Cotelli and Ombretta Pozzoli and Maurizio Colognesi Capogrossi},
  booktitle={PloS one},
  year={2013}
}
AIMS the adult zebrafish heart regenerates spontaneously after injury and has been used to study the mechanisms of cardiac repair. However, no zebrafish model is available that mimics ischemic injury in mammalian heart. We developed and characterized zebrafish cardiac injury induced by hypoxia/reoxygenation (H/R) and the regeneration that followed it. METHODS AND RESULTS adult zebrafish were kept either in hypoxic (H) or normoxic control (C) water for 15 min; thereafter fishes were returned… CONTINUE READING

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Evolution, comparative biology and ontogeny of vertebrate heart regeneration

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