Hypotonic stimulation of the Na+ active transport in frog skeletal muscle: role of the cytoskeleton.

Abstract

Hypotonicity produces a marked activation of the Na+ pump in frog sartorius muscle. The increase in net Na+ efflux under hypotonic conditions occurs despite the reductions in [Na+]i that are due to fibre swelling and Na+ loss. The pump density (ouabain binding) increases not only upon reduction of the medium osmotic pressure (pi) from its normal value (pi… (More)

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Cite this paper

@article{Venosa2003HypotonicSO, title={Hypotonic stimulation of the Na+ active transport in frog skeletal muscle: role of the cytoskeleton.}, author={Roque A Venosa}, journal={The Journal of physiology}, year={2003}, volume={548 Pt 2}, pages={451-9} }