Hypothyroxinemia of prematurity and the risk of cerebral white matter damage.

  title={Hypothyroxinemia of prematurity and the risk of cerebral white matter damage.},
  author={Alan Leviton and Nigel Paneth and M. Lynne Reuss and Mervyn Susser and Elizabeth N. Allred and Olaf Dammann and Karl K. C. Kuban and Linda J. Van Marter and Marcello Pagano},
  journal={The Journal of pediatrics},
  volume={134 6},
OBJECTIVE Infants with hypothyroxinemia of prematurity (HOP) are at increased risk for neurodevelopmental dysfunction. Infants born near the end of the middle trimester are also at increased risk for an echolucency (EL) in the cerebral white matter, which reflects white matter damage and is the cranial ultrasound abnormality that best predicts neurodevelopmental dysfunction. We postulated that some of the increased risk of neurodevelopmental problems associated with HOP reflects an increased… CONTINUE READING

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