Hypothyroidism prevents developmental neuronal loss during auditory organ development

  title={Hypothyroidism prevents developmental neuronal loss during auditory organ development},
  author={Joaquin Rueda and Jorge J. Prieto and Raquel Cantos and Marıx0301a L. Sala and Jaime A. Merch{\'a}n},
  journal={Neuroscience Research},
The deficit of thyroid hormone leads to several structural and physiological modifications in the auditory receptor: the outer hair cells present an immature morphology, abnormal persistence of the afferent dendrites and incomplete development of the efferent terminals. The aim of this work was to perform a quantitative and morphometric study of the spiral ganglion neurons in control and hypothyroid animals. The cochleae from both experimental groups were processed in order to obtain plastic… CONTINUE READING


Publications citing this paper.
Showing 1-9 of 9 extracted citations

Deafness and permanently reduced potassium channel gene expression and function in hypothyroid Pit1dw mutants.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…