Hypothyroidism induces selective oxidative stress in amygdala and hippocampus of rat

Abstract

The effects of hypothyroidism on lipid peroxidation (LP), reactive oxygen species (ROS), and nitric oxide synthase (NOS), levels and expression, in rat brain were examined. Hypothyroidism was induced by administering methimazole in drinking water (60 mg/kg/day). In striatum, motor cortex and cerebellum of hypothyroid rats LP was not modified, whereas LP and… (More)
DOI: 10.1007/s11011-008-9099-0

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