Hypothyroidism in children.

  title={Hypothyroidism in children.},
  author={Debra R. Counts and Surendra K. Varma},
  journal={Pediatrics in review},
  volume={30 7},
1. Debra Counts, MD* 2. Surendra K. Varma, MD† 1. * [] Key MethodAssociate Professor of Pediatrics; Chief, Division of Pediatric Endocrinology, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Md 2. †Editorial Board After completing this article, readers should be able to: 1. Describe the causes of hypothyroidism in infants and children. 2. Discuss the clinical presentation of and diagnostic approach to hypothyroidism. 3. Differentiate nonthyroidal illness low triiodothyronine (T3) syndrome from hypothyroidism. 4…

Tables from this paper

Growth in Autoimmune Thyroiditis: Clinical Features, Controversies, and Outcomes in the Pediatric Population

Though data are few, early discovery and treatment of the disease is felt to avoid significant growth effects, physicians caring for children are encouraged to keep a low threshold for checking thyroid function in children.

Congenital Anomalies in Infant With Congenital Hypothyroidism: A Review of Pathogenesis, Diagnostic Options, and Management Protocols

In addition to exploring the development of CH, this article has also covered the epidemiological data, clinical aspects, and management stemming from pediatric hypothyroidism.

Case 2: Fatigue and Shortness of Breath in an 18-year-old Girl

The patient reports onset of constipation, increasing fatigue, cold intolerance, sad mood, and shortness of breath with exertion, and on further questioning, she reports that she feels light-headed and for the past week has had substernal chest pain that is worse with exertions.

Subclinical hypothyroidism in childhood and adolescense

Abstract Subclinical hypothyroidism (SH) is defined as a serum thyroid-stimulating hormone (TSH) level above the reference range with normal serum free thyroxin (sT4) and free triiodothyronine (sT3)

Agennesis of gland thyroid: a case report and review

The clinical case of a girl attended in the Bolivian Dutch Hospital who was diagnosed congenital to 31 days of life and treatment of substitution was begun with levothyroxina sodium, to avoid the neurological later(posterior) sequels.

Hashimoto Thyroiditis and Dyslipidemia in Childhood: A Review

Characteristics of dyslipidemia in pediatric AIT patients, and the consequences in respect to the risk for cardiovascular disease (CVD) development are discussed, and potential usefulness of novel lipid biomarkers, such as proprotein convertase subtilisin/kexin type 9, are addressed.

Evaluation and management of hypothyroxinemia and hypocortisolemia in preterm neonates: current concepts and contentious issues

Pediatricians, neonatologists and pediatric endocrinologists are often challenged with determining the significance of atypical thyroid and adrenocortical function studies in preterm, low

Identification of Insilico Drugs and Drug Docking Studies on Hypothyroidism and Inferility Disorders in Human

Subclinical hypothyroidism is more common in the elderly, and in Caucasians, while the risk is higher in those with antibodies against thyroid peroxidase.

Iodinated Contrast Agents and Risk of Hypothyroidism in Young Children in the United States

The finding of hypothyroidism in young children exposed to iodine contrast agents is broadly consistent with the sparse literature on this outcome.



Pediatric thyroid testing issues.

While serum thyroid function tests lead to an accurate diagnosis in most patients, unique patient situations can produce misleading results, and heterophile and anti-T4 or anti-TSH antibodies can interfere with accurate T4 or TSH measurement.

Neurodevelopment in infants and preschool children with congenital hypothyroidism: etiological and treatment factors affecting outcome.

It is concluded that even though screened CH children are markedly improved by neonatal diagnosis, they are still at risk for subtle irreversible deficits, which depend on factors such as type, age at onset, and duration of disease.

Thyroid disorders.

  • A. Kahn
  • Medicine, Biology
    The Journal of the Arkansas Medical Society
  • 1984
Thyroid dysfunctions are relatively common among women of reproductive age, and can affect fertility in various ways, resulting in anovulatory cycles, high prolactin levels, and sex hormone imbalances.


  • M. Mcdermott
  • Medicine, Biology
    Annals of Internal Medicine
  • 2009
An expert panel concluded that evidence is insufficient to recommend for or against routine T SH testing but did recommend TSH testing in women with symptoms of thyroid dysfunction, personal or family history of thyroid disease, an abnormal thyroid gland on palpation, or type 1 diabetes mellitus or other autoimmune disorders.

Practical Endocrinology and Diabetes in Children

This concise textbook gives an overview of the relevant physiology and a practical guide to examination, investigation, and management of a broad range of childhood endocrine disorders.

Practical Endocrinology and Diabetes in Children

A large number of patients with these conditions have suffered from at least some of the symptoms of diabetes Mellitus, but their prognosis has improved since treatment.