Hypothyroidism in children.

  title={Hypothyroidism in children.},
  author={D. Counts and S. Varma},
  journal={Pediatrics in review},
  volume={30 7},
1. Debra Counts, MD* 2. Surendra K. Varma, MD† 1. * [...] Key MethodAssociate Professor of Pediatrics; Chief, Division of Pediatric Endocrinology, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Md 2. †Editorial Board After completing this article, readers should be able to: 1. Describe the causes of hypothyroidism in infants and children. 2. Discuss the clinical presentation of and diagnostic approach to hypothyroidism. 3. Differentiate nonthyroidal illness low triiodothyronine (T3) syndrome from hypothyroidism. 4…Expand
Evaluation and management of the child with hypothyroidism
To optimize neurocognitive outcome in infants with congenital hypothyroidism, treatment with levothyroxine should be started as soon as possible, preferably within the first 2 weeks of life, and to ensure normal growth and development as well as cognitive outcome. Expand
Growth in Autoimmune Thyroiditis: Clinical Features, Controversies, and Outcomes in the Pediatric Population
Though data are few, early discovery and treatment of the disease is felt to avoid significant growth effects, physicians caring for children are encouraged to keep a low threshold for checking thyroid function in children. Expand
Subclinical hypothyroidism in childhood and adolescense
Abstract Subclinical hypothyroidism (SH) is defined as a serum thyroid-stimulating hormone (TSH) level above the reference range with normal serum free thyroxin (sT4) and free triiodothyronine (sT3)Expand
Agennesis of gland thyroid: a case report and review
The clinical case of a girl attended in the Bolivian Dutch Hospital who was diagnosed congenital to 31 days of life and treatment of substitution was begun with levothyroxina sodium, to avoid the neurological later(posterior) sequels. Expand
Evaluation and management of hypothyroxinemia and hypocortisolemia in preterm neonates: current concepts and contentious issues
Pediatricians, neonatologists and pediatric endocrinologists are often challenged with determining the significance of atypical thyroid and adrenocortical function studies in preterm, lowExpand
Overt and Subclinical Hypothyroidism
Limited evidence suggests that treatment of subclinical hypothyroidism in patients with serum TSH of up to 10 mIU/L should probably be avoided in those aged >85 years, and over-replacement is common in clinical practice and is associated with increased risk of atrial fibrillation and osteoporosis, and hence should be avoided. Expand
Identification of Insilico Drugs and Drug Docking Studies on Hypothyroidism and Inferility Disorders in Human
Subclinical hypothyroidism is more common in the elderly, and in Caucasians, while the risk is higher in those with antibodies against thyroid peroxidase. Expand
Iodinated Contrast Agents and Risk of Hypothyroidism in Young Children in the United States
The finding of hypothyroidism in young children exposed to iodine contrast agents is broadly consistent with the sparse literature on this outcome. Expand
Differences in the auxological characters of children with short stature - Differential diagnostic possibilities of hypothyreosis.
The study demonstrated the possibility of distinguishing suspected hypothyreosis from other causes of growth retardation based on differences in severity of the ossification delay in skeletal compartments of the hand. Expand
Intraindividual variability of thyroid function tests in a pediatric population.
A population of children with phenylketonuria (PKU) who presented for frequent phlebotomy and laboratory testing (phenylalanine and tyrosine concentrations) pertinent to their follow-up care were identified and residual sample from these individuals were utilized to estimate pediatric intraindividual variability in thyroid function tests. Expand


The Thyroid Gland and its Disorders
The part played by the clinical biochemistry laboratory varies from a relatively minor confirmatory role in the majority of patients, to an important and central role in diagnosis of both adult thyroid disease, when it is mild or at an early stage, and of neonatal disease. Expand
Pediatric thyroid testing issues.
While serum thyroid function tests lead to an accurate diagnosis in most patients, unique patient situations can produce misleading results, and heterophile and anti-T4 or anti-TSH antibodies can interfere with accurate T4 or TSH measurement. Expand
Neurodevelopment in infants and preschool children with congenital hypothyroidism: etiological and treatment factors affecting outcome.
It is concluded that even though screened CH children are markedly improved by neonatal diagnosis, they are still at risk for subtle irreversible deficits, which depend on factors such as type, age at onset, and duration of disease. Expand
Thyroid disorders.
  • A. Kahn
  • Medicine
  • The Journal of the Arkansas Medical Society
  • 1984
Thyroid dysfunctions are relatively common among women of reproductive age, and can affect fertility in various ways, resulting in anovulatory cycles, high prolactin levels, and sex hormone imbalances. Expand
Neurodevelopmental outcomes in congenital hypothyroidism: comparison of initial T4 dose and time to reach target T4 and TSH.
Initial L-thyroxine dose and faster time to normalization of thyroid function are important to optimal neurodevelopmental outcome in severe CH, and it is important to choose an initial dose at the higher end of the recommended range to achieve these goals. Expand
Practical Endocrinology and Diabetes in Children
This concise textbook gives an overview of the relevant physiology and a practical guide to examination, investigation, and management of a broad range of childhood endocrine disorders. Expand
Practical Endocrinology and Diabetes in Children
A large number of patients with these conditions have suffered from at least some of the symptoms of diabetes Mellitus, but their prognosis has improved since treatment. Expand