Hypothyroidism in an area of endemic goiter and cretinism in Central Java, Indonesia.

@article{Goslings1977HypothyroidismIA,
  title={Hypothyroidism in an area of endemic goiter and cretinism in Central Java, Indonesia.},
  author={Bernard M. Goslings and Robert J Djokomoeljanto and Roel Docter and Cornelis van Hardeveld and Georg Hennemann and Dr. R. J. T. Smeenk and Antonio A. M. Querido},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1977},
  volume={44 3},
  pages={
          481-90
        }
}
In an area of severe endemic goiter in Central Java, Indonesia, clinical overt or mild hypothyroidism appeared to be present in 7 out of 20 cretins and also in 12 out of 94 non-cretinous subjects, all 5-20 years of age, living in the village of Sengi. Hypothyroidism was not found in a control group of 70 subjects of the same age living in Londjong just outside the edemia. In hypothyroid subjects the plasma PBI-concentration was 0.98+/-0.32 mug/100 ml (mean+/-SD) vs. 2.72+/-1.24 mug/100 ml in… CONTINUE READING