Hypothesis for resolution of diabetes after sleeve gastrectomy.

  title={Hypothesis for resolution of diabetes after sleeve gastrectomy.},
  author={Wei Zhang and Da-qiao Zhu and Ming Qiu},
  journal={Medical hypotheses},
  volume={79 2},
Sleeve gastrectomy improves glucose metabolism as effective as Roux-en Y gastric bypass. The underlying mechanism is still not clear. We hypothesized that inhibition of GOAT activity was one therapeutic consequence of SG, and a status of low ghrelin level with low AG: UAG ratio might be an optimal gastrointestinal hormone profile for the remission of T2DM.