Hypothesis Testing in Normal Admixture Models to Detect Heterogeneous Genetic Signals

  title={Hypothesis Testing in Normal Admixture Models to Detect Heterogeneous Genetic Signals},
  author={Qian Fan and R. Charnigo and Z. Talebizadeh and Hongying Dai},
  journal={Journal of biometrics \& biostatistics},
In this work we consider a three-component normal mixture model in which one component is known to have mean zero and the other two contaminating components have a nonnegative and a no positive mean respectively, while all three components share a common unknown variance parameter. One potential application of this model may be in prioritizing statistical scores obtained in biological experiments, including genetics data. Such a mixture model may be useful in describing the distribution of… Expand

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