Hypothesis II: Tourette's syndrome is part of a clinical spectrum that includes normal brain development.

@article{Kurlan1994HypothesisIT,
  title={Hypothesis II: Tourette's syndrome is part of a clinical spectrum that includes normal brain development.},
  author={Roger M. Kurlan},
  journal={Archives of neurology},
  year={1994},
  volume={51 11},
  pages={1145-50}
}
Several lines of evidence suggest that the typically associated clinical features of Tourette's syndrome (TS), ie, tics, obsessive-compulsive behavior, inattention, and hyperactivity, commonly occur during childhood development. I hypothesize that TS is expressed in children as a clinical spectrum that includes a range of increasing functional impairment, indicating various degrees of abnormality in basal ganglia development. The mildest form, "developmental" TS, includes largely asymptomatic… CONTINUE READING

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