Hypothesis: preeclampsia is a venous disease secondary to an increased intra-abdominal pressure.

@article{Sugerman2011HypothesisPI,
  title={Hypothesis: preeclampsia is a venous disease secondary to an increased intra-abdominal pressure.},
  author={Harvey J. Sugerman},
  journal={Medical hypotheses},
  year={2011},
  volume={77 5},
  pages={841-9}
}
It is hypothesized that in some women an excessively high intra-abdominal pressure (IAP) compresses the inferior vena cava, uterine veins, portal vein, hepatic veins, splenic vein and renal veins which lead to a decreased flow in these vascular beds, producing lower extremity edema, fetal-placental ischemia, a glomerulopathy with proteinuria and hypertension, hepatic ischemia and thrombocytopenia, increased uric acid, and hemolysis/elevated liver enzymes/low platelet known as the HELLP syndrome… CONTINUE READING

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