Hypothesis: interventions that increase the response to stress offer the potential for effective life prolongation and increased health.

@article{Johnson1996HypothesisIT,
  title={Hypothesis: interventions that increase the response to stress offer the potential for effective life prolongation and increased health.},
  author={Thomas Johnson and Gordon J. Lithgow and Shin Murakami},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  year={1996},
  volume={51 6},
  pages={B392-5}
}
In the last decade it has become evident that many laboratory manipulations, both genetic and environmental, can lead to significant life extension. All or almost all of the observed life-extension phenotypes are associated with increased resistance and/or ability to respond to environmental stress. These observations show dramatically that life span is not maximized. We suggest that latent within many species-perhaps even humans-is the ability for large increases of life expectancy. The… CONTINUE READING