Hypothesis: disseminated intravascular inflammation as the inflammatory counterpart to disseminated intravascular coagulation.

@article{Bull1994HypothesisDI,
  title={Hypothesis: disseminated intravascular inflammation as the inflammatory counterpart to disseminated intravascular coagulation.},
  author={Brian S. Bull and M H Bull},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 17},
  pages={8190-4}
}
We have identified a leukocyte activation syndrome that is occasionally associated with the transfusion of intraoperatively recovered erythrocytes. This syndrome appears to result from intravascular damage caused by leukocytes activated during the erythrocyte salvage process. We hypothesize that this syndrome is part of a larger disease grouping: disseminated intravascular inflammation (DII). DII is the analog of the coagulation disorder disseminated intravascular coagulation. In disseminated… CONTINUE READING