Hypothesis: a role for EBV-induced molecular mimicry in Parkinson's disease.

  title={Hypothesis: a role for EBV-induced molecular mimicry in Parkinson's disease.},
  author={J Woulfe and Madison Tanner Gray and Douglas A. Gray and David Gonz{\'a}lez Mu{\~n}oz and Jaap M Middeldorp},
  journal={Parkinsonism & related disorders},
  volume={20 7},
Current concepts regarding the pathogenesis of Parkinson's disease support a model whereby environmental factors conspire with a permissive genetic background to initiate the disease. The identity of the responsible environmental trigger has remained elusive. There is incontrovertible evidence that aggregation of the neuronal protein alpha-synuclein is central to disease pathogenesis. A novel hypothesis of Parkinson's pathogenesis, articulated by Braak and colleagues, implicates a pathogen… CONTINUE READING
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Exploring the biological significance of molecular mimicry between EBV and alpha-synuclein (Abstract)

  • MT Gray, JJ Tsang, DG Munoz, J. Woulfe
  • Can J Neurol Sci
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2 Excerpts

Influence of LRRK2 G2019 mutation on peripheral B cells from Parkinson’s disease patients

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