Hypothermic effect of cocaine in rats.


Cocaine injected intraperitoneally into rats resulted in a dose-dependent hypothermia. Intracerebral injection of smaller doses also produced a fall in body temperature. In rabbits and guinea-pigs, cocaine produced hyperthermia, in mice and chicks it produced hypothermia while inconsistent changes were produced in goats. Pre-treatment of rats with 6… (More)


Cite this paper

@article{Fahim1975HypothermicEO, title={Hypothermic effect of cocaine in rats.}, author={I Fahim and Mohamad Izwan Ismail and Osman H Osman}, journal={West African journal of pharmacology and drug research}, year={1975}, volume={2 1}, pages={48-56} }