Hypothermia therapy after traumatic brain injury in children.

@article{Hutchison2008HypothermiaTA,
  title={Hypothermia therapy after traumatic brain injury in children.},
  author={J. Hutchison and R. Ward and J. Lacroix and P. Hébert and M. Barnes and D. Bohn and P. Dirks and S. Doucette and D. Fergusson and R. Gottesman and A. Joffe and H. Kirpalani and P. Meyer and K. Morris and D. Moher and R. Singh and P. Skippen},
  journal={The New England journal of medicine},
  year={2008},
  volume={358 23},
  pages={
          2447-56
        }
}
  • J. Hutchison, R. Ward, +14 authors P. Skippen
  • Published 2008
  • Medicine
  • The New England journal of medicine
    • BACKGROUND Hypothermia therapy improves survival and the neurologic outcome in animal models of traumatic brain injury. However, the effect of hypothermia therapy on the neurologic outcome and mortality among children who have severe traumatic brain injury is unknown. METHODS In a multicenter, international trial, we randomly assigned children with severe traumatic brain injury to either hypothermia therapy (32.5 degrees C for 24 hours) initiated within 8 hours after injury or to normothermia… CONTINUE READING
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    References

    SHOWING 1-10 OF 47 REFERENCES
    Treatment of traumatic brain injury with moderate hypothermia.
    • 325
    TREATMENT OF TRAUMATIC BRAIN INJURY WITH MODERATE HYPOTHERMIA
    • OUIS, P. E., +18 authors OSKY
    • 2000
    • 19
    • PDF
    Lack of effect of induction of hypothermia after acute brain injury.
    • 1,283
    • PDF
    Treatment of acute traumatic brain injury in children with moderate hypothermia improves intracranial hypertension
    • 123
    Phase II Clinical Trial of Moderate Hypothermia after Severe Traumatic Brain Injury in Children
    • 289
    Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy.
    • 667
    • PDF
    Hypothermia in the management of traumatic brain injury
    • 179
    Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia.
    • 2,990
    • PDF
    Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest
    • 3,778
    Treatment window for hypothermia in brain injury.
    • 71
    • PDF