Hypothermia therapy after traumatic brain injury in children.

@article{Hutchison2008HypothermiaTA,
  title={Hypothermia therapy after traumatic brain injury in children.},
  author={J. Hutchison and R. Ward and J. Lacroix and P. Hébert and M. Barnes and D. Bohn and P. Dirks and S. Doucette and D. Fergusson and R. Gottesman and A. Joffe and H. Kirpalani and P. Meyer and K. Morris and D. Moher and R. Singh and P. Skippen},
  journal={The New England journal of medicine},
  year={2008},
  volume={358 23},
  pages={
          2447-56
        }
}
  • J. Hutchison, R. Ward, +14 authors P. Skippen
  • Published 2008
  • Medicine
  • The New England journal of medicine
  • BACKGROUND Hypothermia therapy improves survival and the neurologic outcome in animal models of traumatic brain injury. However, the effect of hypothermia therapy on the neurologic outcome and mortality among children who have severe traumatic brain injury is unknown. METHODS In a multicenter, international trial, we randomly assigned children with severe traumatic brain injury to either hypothermia therapy (32.5 degrees C for 24 hours) initiated within 8 hours after injury or to normothermia… CONTINUE READING
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