Hypothermia reduces secretion of vascular endothelial growth factor by cultured retinal pigment epithelial cells.

@article{Coassin2010HypothermiaRS,
  title={Hypothermia reduces secretion of vascular endothelial growth factor by cultured retinal pigment epithelial cells.},
  author={Marco Coassin and Keith G. Duncan and Kathy R. Bailey and Ajay Singh and Daniel M. Schwartz},
  journal={The British journal of ophthalmology},
  year={2010},
  volume={94 12},
  pages={1678-83}
}
AIM Visual loss in age-related macular degeneration usually develops secondary to choroidal neovascularisation. Vascular endothelial growth factor (VEGF) is a critical regulator of retinal angiogenesis and vascular permeability, especially in hypoxic conditions. We hypothesise that hypothermia may reduce the retinal pigment epithelium (RPE) metabolism and… CONTINUE READING