Hypothermia in focal ischemia: implications of experiments and experience.

@article{Kollmar2009HypothermiaIF,
  title={Hypothermia in focal ischemia: implications of experiments and experience.},
  author={Rainer Kollmar and S. Prexler Schwab},
  journal={Journal of neurotrauma},
  year={2009},
  volume={26 3},
  pages={
          377-86
        }
}
Beside aspirin administration and stroke unit care, thrombolysis is the only approved and effective therapy in acute ischemic stroke. Thrombolysis is essentially limited by the short therapeutic window and its potential side effects. Although there is a robust body of evidence on the neuroprotective characteristics of hypothermia in animal models of focal ischemia, the clinical data on hypothermia in stroke are inconclusive in terms of effectiveness. Previous trials suggest that hypothermia is… CONTINUE READING
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