Hypothermia and stroke: the pathophysiological background.

  title={Hypothermia and stroke: the pathophysiological background.},
  author={Bernhard Schaller and Rudolf Graf},
  journal={Pathophysiology : the official journal of the International Society for Pathophysiology},
  volume={10 1},
Hypothermia to mitigate ischemic brain tissue damage has a history of about six decades. Both in clinical and experimental studies of hypothermia, two principal arbitrary patterns of core temperature lowering have been defined: mild (32-35 degrees C) and moderate hypothermia (30-33 degrees C). The neuroprotective effectiveness of postischemic hypothermia is typically viewed with skepticism because of conflicting experimental data. The questions to be resolved include the: (i) postischemic delay… CONTINUE READING


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