Hypothalamic stimulation in chronic cluster headache: a pilot study of efficacy and mode of action.

@article{Schoenen2005HypothalamicSI,
  title={Hypothalamic stimulation in chronic cluster headache: a pilot study of efficacy and mode of action.},
  author={Jean E Schoenen and Laura Di Clemente and Michel Vandenheede and Arnaud Fumal and Victor de Pasqua and Micheline Mouchamps and J. M. Remacle and Alain Maertens de Noordhout},
  journal={Brain : a journal of neurology},
  year={2005},
  volume={128 Pt 4},
  pages={940-7}
}
We enrolled six patients suffering from refractory chronic cluster headache in a pilot trial of neurostimulation of the ipsilateral ventroposterior hypothalamus using the stereotactic coordinates published previously. After the varying durations needed to determine optimal stimulation parameters and a mean follow-up of 14.5 months, the clinical outcome is excellent in three patients (two are pain-free; one has fewer than three attacks per month), but unsatisfactory in one patient, who only has… CONTINUE READING