Hypothalamic sites mediating cardiovascular effects of microinjected bicuculline and EAAs in rats.

@article{Novellis1995HypothalamicSM,
  title={Hypothalamic sites mediating cardiovascular effects of microinjected bicuculline and EAAs in rats.},
  author={Vito de Novellis and E. H. Stotz-Potter and Stephanie M. Morin and Francesca Rossi and Joseph A Dimicco},
  journal={The American journal of physiology},
  year={1995},
  volume={269 1 Pt 2},
  pages={R131-40}
}
Microinjection of gamma-aminobutyric acidA receptor antagonist bicuculline methiodide (BMI) into either the dorsomedial hypothalamic nucleus (DMH) or the nearby paraventricular hypothalamic nucleus (PVN) has been reported to evoke marked tachycardia and modest pressor effects. We compared the effects of microinjecting BMI and excitatory amino acids (EAAs) into 1) the DMH, 2) the PVN, and 3) an intermediate area between the two nuclei. In conscious rats, microinjection of (in pmol) 10 BMI, 0.5… CONTINUE READING

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